AL2O3

Aluminium oxide

Source of the photo: 
https://echa.europa.eu/hu/registration-dossier/-/registered-dossier/16039/1, https://echa.europa.eu/hu/brief-profile/-/briefprofile/100.014.265
Author of the description: 
VE
AL2O3

CHEMICAL SUBSTANCE DATASHEET

 

CHEMICAL SUBSTANCE IDENTIFICATION

Chemical name                 

Aluminum Oxide [1]

Synonyms                           

Aluminium oxide [1], alumina,  aloxide, aloxite, or alundum, depending on particular forms or applications [wiki]

IUPAC name

dialuminum;oxygen(2-) [1], oxo[(oxoalumanyl)oxy]alumane [4]

CAS No

1344-28-1

REACH registration number

 

EC No

Molecular formula              

Al2O3

Substance group/chemical family

mono-constituent substance

Appearance

Physical state

Odour

Form

Colour

 solid

odourless

crystalline powder

white

USES AND HANDLING ISSUES

Relevant identified uses

Production of aluminium, manufacture of abrasives, refractories, ceramics, electrical insulators, catalyst and catalyst supports, paper, spark plugs, crucibles and laboratory wares, adsorbent for gases and water vapors, chromatographic analysis, fluxes, light bulbs, artificial gems, heat resistant fibers, food additive (dispersing agent). Activated alumina is/ an effective desiccant for gases and vapors in the petroleum industry. Also used as catalyst or catalyst carrier in chromatography, and in water purification [1]

Handling considerations

HANDLING
Ensure good ventilation / local exhaust at the workplace in the case of operations generating dust. Avoid creating dusty conditions. Avoid inhalation and skin and eye contact. Wear appropriate personal protective equipment. 
STORAGE
Requirements to be met by store rooms and receptacles: Store in dry ventilated area.
[4]

PHYSICO-CHEMICAL PROPERTIES

Molecular weight                                  

101.961 g/mol [1]

Bulk density/Specific gravity

3.4-4.0 g/cm³ [1] approx. 4 gm/cm3 [4]

pH

 

Particle size

 0.1 - 150 µm for coarse ground alumina, 0.15 - 250 µm for fine unground alumina, and 0.125 - 40 um for fine ground alumina. [4]

EC

 

Melting point

2054 °C [1, 2] 2000 °C [4]

Boiling point

3000 °C [1, 2]  2 980 °C [4]

Flash point

not applicable because  the substance is inorganic [4]

Flammability

 Not combustible [1]

Vapour density

 

Vapour pressure

0 mm Hg (approx) [1, 3], 1 mm at 2158°C [4]

Solubility in water

 insoluble [1], 0.00002 g/L at 20 °C [4]

Solubility in organic solvents

Not applicable because  the substance is inorganic

Solubility in inorganic solvents

Difficult solubility in mineral acids and strong alkali [1], when heated above 800 °C, it becomes insoluble in acid [1] 

Hydrolysis

 

Ionicity in water

 

Surface tension

  because water solubility is below 1 mg/L at 20°C  [4]

Dispersion properties

 

Explosiveness

there are no chemical groups present in the molecule which are associated with explosive properties

Other properties

Very hygroscopic; electrical insulator, electrical resistivity at 300 °C about 1.2x10+13 ohms-cm; very hard, about 8.8 on Mohs' scale [1]

Stability and reactivity

Chemical stability

Stable under normal conditions of use, storage, and transport. [4]

Reactivity hazards

 None [4]

Corrosivity

 

Polimerization

 Ethylene oxide may polymerize violently when in contact with highly catalytic surfaces such as ... the pure oxides of aluminium. [1]

Incompatibility with various substances

 None [4]

Special remarks on reactivity

 

Physical, chemical and biological coefficient

Koc

 

Kow

 

pKa

 

log Kp

 

Henry-constant

 

ENVIRONMENTAL FATE AND BEHAVIOUR

Artificial pollution sources

 

General terrestrial fate

 

General aquatic fate

 

General atmospheric fate

 

General persistence and degradability

 

Abiotic degradation and metabolites

 

Biodegradation and metabolites

According to the guidance given in Annex VII of REACH legislation and Chapter R.7B (Endpoint Specific Guidance) of the ECHA REACH Guidance Document, (2008), the requirements for “Ready biodegradability” can be waived if the substance is inorganic. [4]

Bioconcetration

The available evidence shows the absence of aluminium biomagnification across trophic levels both in aquatic and terrestrial food chains. The existing information suggests not only that aluminium does not biomagnify, but rather that it tends to exhibit biodilution at higher trophic levels in the food chain. [4]

Volatilization

 

Photolysis

 

Hydrolysis

 

Soil adsorption and mobility

 

ENVIRONMENTAL CONCENTRATIONS

Measured data

 

 

ECOTOXICOLOGICAL INFORMATION

General adverse effects on ecosystem

Acute toxicity (LC50, EC50)

Aquatic systems

LC50 (16 days) 430 - 3 910 µg/L, (fish) [4]

LC50 (8 days) 22.4 mg/L, (fish) [4]

LC50 (4 days) 78 - 218 644.1 µg/L, (fish) [4]

LC50 (4 days) 2.9 µmol/L, (fish) [4]]

LC50 (72 h) 10 - 19.3 mg/L, (fish) [4]

EC50 (48 h) 1.5 - 2.56 mg/L, (aquatic invertebrates) [4]

LC50 (4 days) 22 - 30.6 mg/L, (aquatic invertebrates) [4]

LC50 (48 h) 5.7 - 99 600 µg/L, (aquatic invertebrates) [4]

EC50 (4 days) 5.4 - 570 µg/L, (aquatic algae and cynobact) [4]

EC50 (72 h) 16.9 - 4 980 µg/L, (aquatic algae and cynob.) [4]

EC50 (7 days) 8.643 - 15.966 mg/L, (aquatic plants other than algae) [4]

Terrestrial systems

 

Chronic toxicity (NOEC, LOEC)

Aquatic systems

NOEC (60 days) 88 - 350 µg/L, (fish) [4]

NOEC (33 days) 71.5 - 558.1 µg/L, (fish) [4]

NOEC (30 days) 57 - 88 µg/L (fish) [4]

NOEC (28 days) 4.7 - 23.1 mg/L (fish) [4]

NOEC (7 days) 25.1 - 56 480 µg/L, (fish) [4]

NOEC (4 days) 22.6 mg/L, (aquatic invertebrates) [4]

NOEC (48 h) 5 - 672 µg/L, (aquatic invertebrates) [4]

NOEC (42 days) 232.6 - 453.8 µg/L (aquatic invertebrates) [4]

NOEC (30 days) 1.092 - 2.099 mg/L (aquatic invertebrat) [4]

NOEC (28 days) 53.1 - 4 281.8 µg/L (aquatic invertebrat) [4]

NOEC (21 days) 76 - 600 µg/L (aquatic invertebrates) [4]

NOEC (17 days) 962.5 µg/L (aquatic invertebrates) [4]

NOEC (72 h) 4 - 600 µg/L, (aquatic algae and cynobact) [4]

LOEC (72 h) 400 - 1 000 µg/L, (aquatic algae and cynob.) [4]

NOEC (7 days) 2.76 mg/L (aquatic plants other than algae) [4]

NOEC (4 days) 45.7 mg/L (aquatic plants other than algae) [4]

LOEC (7 days) 5.314 mg/L (aquatic plants other than algae) [4]

Terrestrial systems

 

HUMAN HEALTH EFFECTS and PROTECTION

Routes of human exposures

inhalation, oral 

General effects

 

Endocrine disruption

 

Mutagenicity

 

Carcinogenicity

 

Reprotoxicity

 

Teratogenicity

 

Skin, eye and respiratory irritations

 

Metabolism:

absorption, distribution & excretion

 

Exposure limits

 For workers: inhalation: (DNEL) 15.63 mg/m³ (both long term systemic and local effects) [4]

For general population: oral: (DNEL) 3.29 mg/kg bw/day (long term, systemic effects) [4]

 

Drinking water MAC

 

Other information

 

 

 

 

 

Animal toxicity data

Acute toxicity (LD50)

LD50 10 000 - 15 900 mg/kg bw (rat, oral)  [4, 5]

LC50 (4 h) 888 - 2 300 mg/m³ air (rat, inhalation) [4, 5]

LC50 (60 min) 7.6 mg/L air (rat, inhalation) [4, 5]

LC0 (4 h) 888 mg/m³ air (rat, inhalation) [4, 5]

Chronic toxicity (NOEL, LOEL)

NOAEL (rat, oral): 200 - 3 225 mg/kg bw/day [4, 5]

NOAEL (rat, oral): 141 - 302 mg/kg diet [4, 5]

NOAEL (dog, oral): 1 034 - 1 087 mg/kg bw/day [4, 5]

NOAEL (dog, oral): 90 mg/kg diet [4, 5]

NOAEC (rat, inhalation): 70 mg/m³ air [4, 5]

ENVIRONMENTAL STANDARDS AND REGULATIONS

EINECS regulation

̵listed by EINECS (European INventory of Existing Commercial chemical Substances) List [4]

OSHA regulations etc.

 

 

 

OTHER INFORMATION, SPECIAL REMARKS

Classification and proposed labelling with regard to toxicological data

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed and is harmful if inhaled. [4]

 

 

CREATED, LAST UPDATE

Created

2019. 08. 26

Last update

2019. 09. 02

REFERENCES

 [1] PubChem, Aluminium oxide, https://pubchem.ncbi.nlm.nih.gov/compound/Aluminum-oxide#section=CAS, Accessed 2019.08.26

[2] ILO International Chemical Safety Cards (ICSC), http://www.ilo.org/dyn/icsc/showcard.display?p_version=2&p_card_id=0351,  Accessed 2019.08.26

[3] Occupational Safety and Health Administration (OSHA),  α-ALUMINA (ALUNDUM), http://www.osha.gov/chemicaldata/chemResult.html?RecNo=242,  Accessed 2019.08.26

[4] ECHA, https://echa.europa.eu/hu/registration-dossier/-/registered-dossier/16039/1, https://echa.europa.eu/hu/brief-profile/-/briefprofile/100.014.265,  Accessed 2019.08.30

[5]European Commission, ESIS; IUCLID Dataset, Aluminum oxide (1344-28-1) p.61 (2000 CD-ROM edition). Available from, as of April 26, 2010: http://esis.jrc.ec.europa.eu/  Accessed 2019.08.26