Etridiazole, a fungicide

• CAS No. 2593-15-9
• Chemical Name: ETRIDIAZOLE
• Synonyms: ETMT; ;Dwell; Koban; TRUBAN; Banrot; Etcmtb; MF-344; om2424; ETHAZOL
• CBNumber: CB0145031
• Molecular Formula: C5H5Cl3N2OS
• Formula Weight: 247.53
• MOL File: 2593-15-9.mol

• Fp : 154.5 °C
• storage temp. : 0−6°C
• Safety
• Hazard Codes : T,N
• Risk Statements : 21/22-23-40-50/53-20/21/22
• Safety Statements : 36/37-38-45-60-61
• RIDADR : UN2810 6.1/PG 2
• RTECS : XI3875000

Etridiazole is a soil treatment substance used  against seedling and other diseases on field crops, vegetables and ornamentals. It interferes with lipid and membrane synthesis in fungi.

Types of formulation: wettable powder, emulsifiable, concentrate.

Environmental Fate
Etridiazole is a mobile compound with moderate persistence and high
volatility. At the relatively low application rates for cotton, ornamental plants and
seed treatment, it is not expected to pose risks for surface or ground water.
However, the application rates for golf course turf are 50 times higher than for the
other crops. Because etridiazole is stable to hydrolysis and aqueous photolysis, it
may persist for considerable periods of time in the aquatic environment.
Ecological Effects
Etridiazole use on golf course turf is a concern, given the relatively high
application rates for turf and the likelihood of golf course runoff to move toward
surface water.
On an acute basis, etridiazole is practically non-toxic to birds, slightly toxic to
mammals, moderately toxic to fish and aquatic invertebrates, and highly toxic to
non-target aquatic plants. Available data indicate that the degradate 3-
dichloromethyl-5-ethoxy-1,2,4-thiadiazole is highly toxic to aquatic organisms.
In-furrow application to cotton presents no acute risks to birds, mammals,
fish or aquatic invertebrates. However, acute risks are a concern for aquatic
plants. Chronic risks from use on cotton are a concern for birds; however, no
acceptable chronic mammalian data were available, so a chronic risk assessment
for mammals could not be conducted. Use on golf course turf results in acute risks
for birds, mammals, fish, aquatic invertebrates and aquatic plants. Chronic risks
are a concern for birds and aquatic organisms. There are risks to federally listed
endangered and threatened birds, mammals, aquatic plants and freshwater and
estuarine fish and invertebrates from single and multiple applications of etridiazole
to turf. Chronic effects seen in laboratory studies include significant reproductive
effects in birds and limited growth in fish. As previously indicated, a chronic risk
assessment for mammals could not be conducted due to a lack of data.

Toxicty:

• Mammal (rat) LD50 Oral: 1077 mg/kg − Slightly toxic
• Mammal (rabbit) LD50 Dermal: >5000 mg/kg − Slightly toxic
• Bird (quail) LD50 560 mg/kg − Slightly toxic
• Bees (contact) No data available
• Fish (trout) (96 hour) LC50 >4.0 mg/L − Moderately toxic
• Worms (14 days) No data available 

Safety:

• Harmful if swallowed, inhaled or absorbed through skin.
• Wear protective clothing and respirator.
• Wash contaminated skin with soap and water.
• Flush contaminated eyes with large amounts of fresh water for 15 minutes.
• Safety data and registration of this active ingredient are under review.

Environmental considerations:

• Etridiazole is a mobile compound with moderate persistence and high volatility.
• Etridiazole may persist for considerable periods of time in aquatic environments.
• Toxic to fish and highly toxic to nontarget aquatic plants. Do not apply directly to, or contaminate water with cleaning or disposal.
• Non-phytotoxic when used as directed.
• Etridiazole is practically non-toxic to birds, and is slightly toxic to mammals.